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KMID : 1157520190150020103
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International Journal of Clinical Preventive Dentistry
2019 Volume.15 No. 2 p.103 ~ p.107
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Changes in Saliva Composition before and after Use of Mouthwash Containing Green Tea Extract
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Park Jung-Eun
Jang Jong-Hwa
Hwang Su-Yeon
Kim Da-Hui
Cho Ja-Won
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Abstract
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Objective: The goal of this study was to evaluate the efficacy of green tea extract (GTE) in reducing oral bacteria by analysis of saliva composition before and after using mouthwash containing GTE.
Methods: This study measured organic acids (lactate, acetate, propionate, formate, butyrate, pyruvate, valerate) found in the saliva of 15 healthy adults before and 1, 2, and 4 weeks after use of GTE mouthwash. A Dionex ion chromatography system was used for analysis. During the mobile phase, NaOH 100 mM was applied through isocratic elution.
Results: Changes in saliva composition compared to a control after the use of mouthwash containing GTE, included an increase in lactate during the first and second week followed by a decrease of 0.48 mM (82.74%) in the fourth week. Acetate slightly increased by 0.03 mM (0.46%) compared to the control. Propionate, formate, butyrate, and pyruvate increased 0.11-1.55 mM after four weeks compared with the control. Valerate was not detected.
Conclusion: Seven organic acids were compared. Only lactate decreased after use of the GTE mouthwash. Therefore, the GTE mouthwash in this study has the potential to inhibit the growth of some oral bacteria.
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KEYWORD
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Camellia sinensis, lactic acid, oral health, saliva
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